CBD vs THC: What's the difference?

What is the difference in CBD and THC? 

Both are chemically similar to the endocannabinoids that the body can naturally produce, therefore both CBD and THC can interact with the body’s cannabinoid receptors

When these receptors are stimulated, they can release neurotransmitters throughout the body. 

Neurotransmitters play an important role in regulating sleep cycles, moods, and muscle movement by acting as messengers between cells and neurons. 

Although both compounds can stimulate our cannabinoid receptors and trigger the release of neurotransmitters, CBD and THC can affect our bodies in different ways.


  • Stands for Cannabidiol
  • Can be derived from cannabis OR hemp plant
  • Non-psychoactive (does not make you “high”)
  • Hemp-Derived CBD is legal on the federal level
  • Can have potential health benefits that are still being studied 
  • Is not typically screened for in drug tests


  • Stands for Tetrahydrocannabinol
  • Found in cannabis (marijuana) plants 
  • Trace amounts (0.3%) can be found in legal hemp products
  • Induces a psychoactive effect 
  • Not legal on the federal level
  • Legal medicinally in 33 states
  • Legal recreationally in 15 states, plus Washington D.C.
  • Is a typical component to screen for in a drug test 

Both CBD and THC are sold in a number of different forms including smokeable flower, pre-rolls, concentrated oils, tinctures, lotions and balms, infused candies, and chewing gums so there is certainly a variety in both categories. 

SYNAPSE® CBD Gum uses a Hemp-Derived, Broad-Spectrum CBD which is water-soluble and contains no traces of THC, as this is removed during the extraction process. The Certificate of Analysis can be viewed here.

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